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However, in terms of MASLD, short-acting agents still hold potential clinical advantages

Increasing resting energy expenditure (REE): Raises REE, meaning the body burns more calories at rest [11]

Localized Fat Reduction : Targets areas of high fat accumulation, such as the abdomen, thighs, buttocks and hips

The two-domain binding mode suggests that the C-terminus of the peptide hormone initiates recognition with the ECD

Abbreviations ALK: Anaplastic lymphoma kinase ALL: Acute lymphoblastic leukemia EGF: Epidermal growth factor ER: Estrogen receptor FAK: Focal adhesion kinase FGF: Fibroblast growth factor HGF: Hepatocyte growth factor HNSCC: Head and neck squamous carcinoma IGF: Insulin-like growth factor IGFBP: IGF-binding protein IGF-IR: Type I insulin-like growth factor receptor IGF-IIR: Type II IGF receptor InsR: Insulin receptor mAbs: Monoclonal antibodies MAPK: Mitogen-activated protein kinase PDGF: Platelet-derived growth factor PI3K: Phosphatidylinositol 3-kinase RTK: Receptor tyrosine kinase TGF: Transforming growth factor VEGF: Vascular endothelial growth factor References Bach LA

5 Calibration curve prepared using pseudo-end point method